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The second blood sample from each patient was centrifuged at 3500 rpm for 5 min at 4 C in a refrigerated centrifuge and plasma was collected, aliquoted and stored at 80 C for measurements of the following below biomarkers

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In 2018, a more immunogenic EBV VLP was created by fusing EBNA1 and EBNA3C to the EBV tegument protein BNRF1