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It is well-documented that radiotherapy induces cancer cell apoptosis by DNA damaging

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Fish JE, Yan MS, Matouk CC, St Bernard R, Ho JJ, Gavryushova A, Srivastava D, Marsden PA (2010) Hypoxic repression of endothelial nitric-oxide synthase transcription is coupled with eviction of promoter histones

Acids 30 , 479492 (2022)

Follow-up visits: mid-window and end-of-window, in person or hybrid depending on stability

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AP demonstrates potential therapeutic efficacy in MM management, though its toxicity profile and adverse effects warrant critical consideration, particularly regarding cellular, reproductive, and renal impacts