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Additional factors including patients preference and administration route must be also taken in consideration

The aromatase inhibitor, letrazole, delayed the onset of tumor formation

And so we can just navigate the middle that way

LncRNA P53RRA can bind to Ras GTPase activating protein binding protein 1 (G3BP1) to activate the p53 pathway and retain more p53 in the nucleus, thereby exerting a pro-ferroptosis effect [170]

[DOI] [PMC free article] [PubMed] [Google Scholar] 75.Moore JJ, Saadabadi A

Although it has been suggested that metformin treatment may exert a synergistic antitumor effect with ICIs, the study by Jacobi et al (107) did not obtain any positive association between metformin and ICIs in the treatment of patients with diabetes combined with NSCLC