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Intriguingly, mitochondrial Ca 2+ overload itself contributes to mitochondrial dysfunction and ROS generation (136, 137)

doi: 10.1093/ajcn/59.3.654 136

Make sure you follow your healthcare providers advice and recommendations

Adipocytes and bone marrow stromal cells in the TME can promote the resistance of tumor cells to ASNase treatment by supplying Gln and cysteine to leukemia cells, 348,349 and cancer-associated fibroblasts can secrete Asp to promote solid tumor growth