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In the first stage, each model was constrained to obtain an optimal fit to the gene expression signature of the cell line by solving a Mixed Integer Linear Programming problem, via the integrative Metabolic Analysis Tool (iMAT) 32,33

IVIG treatment is a key part of many of these plans, providing steady immune system support and helping control flare-ups

Lysosomal staining of PA-TU-8902 cells with LysoTracker Green exposed to C-phycocyanin (0.2 M, 20 h incubation)

One cluster has a well-established role in mediating a radical SAM reaction

However, 72% of the controls had no posterior teeth, and the remainder had a mean of only three teeth

100 mM triethylammonium bicarbonate, TEAB