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In the fission yeast Schizosaccharomyces pombe , deficiency of mitochondrial superoxide dismutase SOD2 accelerates chronological aging

[ref] The glutamate-cysteine ligase (GCL) enzyme interacts with glutamate and cysteine, resulting in the formation of gamma-glutamylcysteine

2000 Oct;136(4):270-6

Epigallocatechin-3-gallate is a potent phytochemical inhibitor of intimal hyperplasia in the wire-injured carotid artery

found that these two vectors were highly expressed in myocardial mitochondria and showed that inhibition of DIC and OGC increased mitochondrial ROS and GSH depletion, exacerbating ferroptosis in the myocardium [60]