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[4] [5] [6] Post-marketing use of azelaic acid has been associated with the development of hypersensitivity reactions (including angioedema, ocular inflammation, facial swelling, and urticaria) and asthma exacerbation (i.e., dyspnea, wheezing)

If the vial was at temperatures above 86 degrees F for any significant period (more than a few hours): the risk of meaningful degradation is high

16 Despite widespread use of supplements, most patients are ill-informed about potential adverse interactions