Recruitment for ME/CFS patients started just before COVID related restrictions were introduced and research was suspended: one patient and one healthy control were recruited in February 2020, others from February 2021
Abbreviations ADHD: Attention deficit hyperactivity disorder ALA: Alpha-linolenic acid ANCOVA: Analysis of covariance BW: Body weight BMI: Body mass index CONSORT: Consolidated Standards of Reporting Trials CH: Cluster headache DASS-21: Depression, Anxiety, Stress Score HDR: Headache diary score HIT-6: Headache impact test-6 CRP: C reactive protein ICDH -3: International Classification of Headache Disorder III IL-6: Interleukin-6 IRCT: Iranian Registry of Clinical trial IPAQ: International Physical Activity Questionnaire LC: L-carnitine MDA: Malondialdehyde MHIS: Migraine headache index score MOH: Medication overuse headache MSQ: Migraine Specific Quality of Life NF- B: Nuclear factor kappa B NO: Nitric oxide PA: Physical activity PSQI: Pittsburg Sleep Quality Index QOL: Quality of life SPIRIT: Standard Protocol Items Recommendations for Interventional Trials SD: Standard Deviation SOD: Superoxide dismutase TAC: Total antioxidant capacity TNF-: Tumor necrosis factor-alpha TTH: Tension type headache VAS: Visual analog scale References Celikbilek A, Sabah S, Tanik N, Ak H, Atalay T, Yilmaz N
Urolithiasis 50, 711720
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menaquinone-7 (vitamin K2) from Bacillus subtilis natto, cholecalciferol (vitamin D3), soy (from natto fermentation) Recommended Use: Take 1/2 tablet daily, preferably 30 minutes before a meal, with water
