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In an era where a variety of different therapeutic options is the norm for the management of chronic diseases such as type 2 diabetes and hypertension, the hope is that this process will led to better personalized anti-obesity treatments, focusing on the special characteristics, needs, and comorbidities of each patient and the effectiveness and safety of the recommended therapy

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However, the virulence and uncontrollable immune response of bacteria greatly limit the clinical trial and application of bacterial therapy

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