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Minimizing unnecessary polypharmacy, such as NSAIDs and loop diuretics, is essential to prevent adverse drug reactions, particularly in elderly patients who require close monitoring

Conversely, necroptotic NSCs initiate a compensatory TSC2mTORautophagy axis through exosome transfer, which is predicted to enhance debris clearance

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It is anticipated that these possibilities will be resolved in the very near future

However, when the 5-HT-releasing agent D-fenfluramine is used in patients experiencing a neurobehavioral syndrome after exposure to organophosphates, elevated sensitivity of central 5-HT receptors is observed (442)