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DUSP9 (MKP4) DUSP9 (also named as MAPK phosphatase 4, MKP4) is a typical DUSP that inhibits the activation of ERK, p38, and JNK [151, 177,178,179]

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Correctly targeted ES clones were injected into albino C57BL/6 J blastocysts, and the resulting chimeric founders were bred with C57BL/6 J females to establish germline-transmitting heterozygous mice, hereafter referred to as HDAC9-Tg flox-STOP-flox mice (Fig