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Short-chain fatty acids (SCFAs) can activate specific signaling pathways in the host and regulate hormone secretion by affecting gut motility and fat storage in adipose tissue [20]

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As shown in Figures 5L, M, Fer-1 significantly reversed the effect of Sat1 over-expression on TFR1 and GPX4 protein expression, but it did not affect the protein expression of SAT1, which also demonstrated that SAT1 was the upstream regulator of ferroptosis

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Common dysfunctional variants in ABCG2 are a major cause of early-onset gout

Notably, GGsTop treatment blocked GGT activity and slowed tumour growth without causing any overt toxicity to animals (Fig