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Rating: 4.8298000000000005 (9 reviews)

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These characteristics contribute to enhanced colloidal stability, prolonging the NPs' half-life in the systemic circulation, reticuloendothelial (RES) system clearance, and promoting passive accumulation of the NPs within tumor tissue 41

Depletion of cystine/cysteine reduces intracellular GSH levels and GPX4 activity within the cystine/cysteine-GSH-GPX4 axis, thus causing ferroptosis (18,99)