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In particular, the PI3K/AKT axis converts phosphatidylinositol-4,5-bisphosphate (PIP 2 ) to phosphatidylinositol 3,4,5-trisphosphate (PIP 3 )

2023;120:e2214853120

BMC Microbiol 8:112 Hall M, Grundstrm C, Begum A, Lindberg MJ, Sauer UH, Almqvist F, Johansson J, Sauer-Eriksson AE (2016) Structural basis for glutathione-mediated activation of the virulence regulatory protein PrfA in Listeria

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In this study, the intestinal microenvironment was recapitulated by applying defined mechanical deformations and fluid hydrodynamics, exploiting a coculture with a host microbiome while allowing the real-time monitoring of cell morphology and cell-cell interactions, in a manner not possible with a standard organoid culture

Glutathione reductase (GR) which catalyzes the reduction of GSSG using NADPH as a reductant is also a glutathione-linked enzyme involved in cell protection