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Ogawa, M., Hiraoka, Y

The use of Schisandra in Russia as an adaptogen was also solidified during the 20th century, where it was taken by hunters and athletes to reduce hunger, thirst, and exhaustion

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To induce PCOS, the rats were administered dehydroepiandrosterone (DHEA) (Sigma, 6 mg/100 g body weight dissolved in 0.2 ml sesame oil) via subcutaneous injection for 21 consecutive days 24,53,54

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The differential diagnosis is broad, from diabetes to B12 deficiency to autoimmune conditions to malignancy, and treatment varies dramatically by cause