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Description

The addition of bevacizumab, a monoclonal antibody to VEGF-A, to the platinum-based doublets is currently used for first-line therapy for advanced and unresectable NSCLC except in the case of squamous cell carcinoma (3)

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Overall, AOD-9604 appears safe, with a profile similar to a placebo

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The important role of histone deacetylases in modulating vascular physiology and arteriosclerosis

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Moreover, this synthetic lethality is particularly pronounced in BRCA-deficient tumors, where HR is already compromised

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