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Consequently, the balance between system Xc and glutamate transport is disrupted, leading to both a reduced intracellular uptake of glutamate and an inhibition of GSH synthesis due to the lack of necessary raw materials (87)

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It also activates sirtuins and has shown promise in improving mitochondrial function and reducing inflammation in the brain [reference needed, not in list]

10.1016/j.jtocrr.2025.100807 105 SmeekensS

CrossRef Relationship Between Body Mass Index and Low Skeletal Muscle Mass in Adults Based on NHANES 20112018 Rong-Zhen Xie, Xu-Song Li, Fang-Di Zha, Guo-Qing Li, Wei-Qiang Zhao, Yu-Feng Liang, Jie-Feng Huang Scientific Reports .2025;[Epub] CrossRef Predictors of Sarcopenia in an Obese Asian Population Min Je Sung, Jun Yong Park, Hye Won Lee, Beom Kyung Kim, Do Young Kim, Sang Hoon Ahn, Seung Up Kim Nutrition and Cancer .2022

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