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We used the engineered heme peroxidase APEX2 as a chemogenetic tool to generate free radicals and drive lipid oxidation

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Rev Environ Contam Toxicol : 137 Mukhopadhyay R, Bhattacharjee H, Rosen BP (2014) Aquaglyceroporins: generalized metalloid channels

Therefore, redox regulation is involved in the occurrence and progression of various diseases at multiple levels and is expected to become a key entry point for therapy

Pyruvate Dehydrogenase PDH-E1beta Controls Tumor Progression by Altering the Metabolic status of cancer cells

Supraphysiological testosterone concentrations have been shown to reduce endothelial nitric oxide synthase expression and nitric oxide bioavailability, thereby favouring vasoconstriction and increased arterial stiffness ( Oxidative stress appears to represent a central mechanistic pathway linking molecular signalling alterations with structural cardiac pathology