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Description

Proinflammatory cytokines were increased in subjects with ALD vs without and significantly elevated vs controls

Concurrently, enhanced KP activity depletes TRP availability for 5-HT synthesis, weakening serotonergic inhibition of the amygdala, which in turn facilitates HPA axis activation [134]

GHK-Cu works through cumulative tissue exposure, not peak concentration

The limitations of the current study include the lack of critically ill ventilated ICU patients (as participants had to be able to provide consent), the lack of multiple longitudinal sampling and small sample size