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PPD usually occurs within 6 weeks of childbirth and affects up to People are more at risk of developing PPD if they have a history of depression or anxiety, had a high risk or complicated pregnancy, have limited social support, get limited sleep, or are physically inactive

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Johns Wort may decrease a medications effectiveness: Most SSRIs are extensively metabolized by liver enzymes, and supplements that affect these enzymes could potentially change the way your body eliminates SSRIs, Cole says

Lack of effectiveness following treatment may be due to a myriad of factors