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Antioxidants 11(4):643 Chen J, Yu H, Tan X et al (2023) PFKFB3-driven vascular smooth muscle cell glycolysis promotes vascular calcification via the altered FoxO3 and lactate production

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The enormous selective advantage of red blood cells with normal hemoglobin or anti-sickling hemoglobin predicts that genetic modification of a proportion of HSCs (estimated 1020%) may suffice as a one-off treatment (ClincialTrials.gov Identifier: NCT02963064)

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