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EM, SA, and HT: contributed to data collection and figures designing

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doi: 10.1080/08039480701643290, 61

Firstly, the results of safranin O-fast green staining and HE staining suggest that the cartilage degeneration induced by continuous HFD, which was reversed by intra-articular injection of lentivirus expressing FOXO3, reappeared with a deteriorating trend after injection of small interfering RNA targeting FOXO3 (Supplementary Fig

However, there is no established direct causal link between vitamin B12 and joint pain in the medical literature

In the USA, the maximum dosage per day recommended by the manufacturer (MacNeil Consumer Healthcare) was reduced from 4000 mg (eight 500 mg pills) to 3000 mg (six 500 mg pills) in 2011[35]