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Data in global ARKO mice showed that functional AR signaling was important for maintenance of maximum force production in EDL but not soleus [178], and maintenance of sex differences in muscle-specific fatiguability and sprint time to exhaustion [178, 188] in young adult mice

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Although the mechanisms underlying this association were not exactly defined, investigations suggested some pathways to clarify the related mechanisms

WHY, WHO, AND WHEN TO DEPRESCRIBE WHY: Older Adults Have Specific Needs Since older adults have differing health and functional statuses, prescribers must individualize medication selection for these patients