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Oxidative stress and inflammation are major contributors to premature skin aging, leading to the formation of fine lines, wrinkles, and uneven skin tone

Mitochondrial dysfunction underlies cognitive defects as a result of neural stem cell depletion and impaired neurogenesis

Similarly, in 5FAD transgenic mice, GPX4 overexpression improves cognition, reduces neurodegeneration, lowers LPO levels, and decreases A production (300)

In normal, healthy cells, 90% of ROS are generated as a result of cellular respiration

When proteins tagged with ubiquitin bind to the proteasome, the ubiquitin tag is removed and the proteins are broken down into smaller pieces

Vitamin B12 deficiency can be easily detected with a blood test and is easily treatable with a daily supplement