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Suicidal Thinking and Behavior Counsel patients, their caregivers, and families that AEDs, including divalproex sodium delayed-release capsules, may increase the risk of suicidal thoughts and behavior and to be alert for the emergence or worsening of symptoms of depression, any unusual changes in mood or behavior, or the emergence of suicidal thoughts, behavior, or thoughts about self-harm

Kahn SE, Hull RL, Utzschneider KM (2006) Mechanisms linking obesity to insulin resistance and type 2 diabetes

Notably, patients with the highest genetic loading for acetylcholine pathway variants are about three times more likely to respond well to lithium than those with the lowest loading [4, 99]

Thromb Haemost 109:10991107

Conversely, recent achievements in the fabrication of diverse nanoscale materials with high capacity for localized drug delivery have opened another avenue in the treatment of CNS-related disorders such as MS

"It could ultimately result in someone's death," he said