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279 SIRT1 deficiency impairs autophagy induction under nutrient-deprived conditions, leading to metabolic imbalance and cellular stress

The nuclear protein fraction was extracted, and the relative Dnmt and 5-mC hydroxylase Tet activities were calculated based on the ratio of the treatment group to the control group after the normalization to the amount of protein

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The decomposition of HO by CAT activity was measured by monitoring the absorbance at 240 nm over a period of 2 min

[DOI] [PMC free article] [PubMed] 207.Fitz NF, Nam KN, Koldamova R, Lefterov I

Cell 80 , 293299 (1995)