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Mouse model of periventricular leukomalacia A model of neonatal brain injury, which reliably resembles the neuropathology of PVL, 19, 20 was induced in P6 mouse pups using ischemia induced by unilateral carotid ligation (UCL) and followed by hypoxia, which resulted in selective injury to the periventricular white matter

Rotate injection sites to minimize irritation

Dietary deficiency: Strict vegans or very poor diets may lack animal-source B12

While B12 can be obtained through dietary sources, some individuals may suffer from deficiency due to difficulty absorbing the vitamin properly

The information remains unclear on vitamin B 12 supplementation and the information we have is mainly from older studies