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PMID: 21507583

The combination of soy cerebrosides and LDLR can block LDL endocytosis, and curcumin can inhibit HIF-1 nuclear translocation

Cell Death Differ 30:208220 Abutin RM, Chen J, Lung TK, Lloyd JA, Sawyer ST, Harada H (2009) Erythropoietin-induced phosphorylation/degradation of BIM contributes to survival of erythroid cells

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The inflammatory response initiated by these translocated materials is particularly significant since circulating inflammatory mediators can interact directly with the bloodbrain barrier (BBB), leading to increased BBB permeability