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MicroRNA-124: a key player in microglia-mediated inflammation in neurological diseases

Research showed that activation of GPX4 was able to suppress inflammation, including cellular ROS level reduction and NF-B pathway suppression, and suggested boosting GPX4 activity could be considered a novel anti-inflammatory strategy in lipid peroxidation-associated diseases (Li et al., 2018)

Mitochondria (the power plants inside cells) dont work well in neuropathy, which lowers energy (ATP) and produces harmful molecules called free radicals

Due the high number of cells possibly involved at the level of the organism and its lifespan, the probability of cancer and metastasis remains high

EBioMedicine 23, 100110

9 ((a) control