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10.12659/MSM.922634 63 PengW

The DMSs were then categorized based on their location within the gene body according to the reference genome obtained from the UCSC, 40% of DMSs were found within introns, 36% within intergenic regions, 13% in exons, and 11% within promoters

OTUs, overlapping operational taxonomic units

To a lesser extent, Chinese, other Asians, and African Americans can also be affected [73]

Consequently, we delve into the molecular mechanisms through which 16-OHE promotes PH, encompassing induction of oxidative stress, enhancement of proliferation and migration of pulmonary arterial smooth muscle cells (PASMCs) and pulmonary arterial endothelial cells (PAECs), promotion of metabolic abnormalities, induction of endothelial mesenchymal transition (EndoMT), and fostering inflammation (Fig

Other cytokines and chemokines CCL20 is one of the most significantly upregulated chemokines in patients with AH [73] and is associated with endotoxemia, liver fibrosis, and short-term mortality [154]