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CaM, in its Ca 2 -bound form (Ca 2+ -CaM), is required for activating eNOS by facilitating electron flow from the reductase domain to the oxygenase domain and promoting dimerization of the latter (Forstermann et al., 1991

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The presence of amyloidoligomers (AO) is closely correlated to the incidence of AD

The relationship between GPX and Zn supports the trace element dependency of glutathione peroxidase activity, and the correlation of NDUFS6 with Cl implies mitochondrial adaptation to ionic imbalance during dehydration and acidosis 118

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