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To better elucidate the causal link, the review will also touch on the molecular mechanisms pertaining to the observed effects followed by the tight-knit relationships between (poly)phenols and the gut microbiota

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Mutations in the LRRK2 gene, particularly the most common Gly2019Ser mutation, are seen in patients with autosomal-dominant PD and patients with apparently sporadic PD, who are clinically indistinguishable from patients with idiopathic PD [100]

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Such biomarkers could help identify patients most likely to respond to treatment and could facilitate personalized treatment approaches