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The generalizability of findings is also often limited by insufficient consideration of individual differences, such as genetic background, baseline nutritional status, gut microbiota composition, and specific OA phenotypes (e.g., metabolic vs

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Yes, B12 plays a role in cell production and repair, which contributes to healthier hair growth, stronger nails, and clearer skin

The NAD+ salvage pathway can work more efficiently, boosting intracellular NAD+ levels

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Each SNP information is available from the id number of dbSNP on the National Center for Biotechnology Information (NCBI) repository ( The genetic datasets generated and/or analyzed during the current study are provided in the SNPs data of the Additional file 1