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All statistical analyses were performed using R version 4.1.1 (R Foundation for Statistical Computing)

Figure 2 Although environmental determinants of male infertility originate from diverse sources including airborne particulates, heavy metals, endocrine-disrupting chemicals, microplastics, and temperature changes they cannot be an isolated threat (21)

Moreover, it holds significant promise as an ND treatment, but future research should focus on increasing bioavailability and understanding its long-term clinical effects

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There is an overall lack of evidence for clear benefit of glucocorticoids, but it is frequently used