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Fosgonimeton failed its Phase 2 ACT-AD trial in 2022 and its Phase 2/3 LIFT-AD trial in September 2024

Studies have also found improvements in cognitive tasks and reduced brain fog among users

Expression of methylthioadenosine phosphorylase cDNA in p16-, MTAP- malignant cells: restoration of methylthioadenosine phosphorylase-dependent salvage pathways and alterations of sensitivity to inhibitors of purine de novo synthesis