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Plant 8, 674676

Inhibitor binding in a class 2 dihydroorotate dehydrogenase causes variations in the membrane-associated N-terminal domain

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doi.org/10.1111/acel.12784 Ben-Meir A, Burstein E, Borrego-Alvarez A, et al

Summary of molecular imaging studies in late-life depression With respect to neurotransmitter deficits in LLD, pre-synaptic serotonergic deficits are observed, especially in cortical and limbic regions, while post-synaptic receptors (5-HT1A, 5-HT2A, 5-HT4) are affected to a limited extent, in contrast to MCI, AD and PD that show more widespread pre and post- synaptic serotonin deficits