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These TMT transporters are encoded by genes within the solute carrier (SLC) transporter gene family, which comprises over 300 genes that regulate the translocation of various substrates across the BBB [39]

Some studies suggest that CNTF may indirectly contribute to microglial activation, especially during chronic inflammation or injury, but it is not a classical microglial activator, such as IL-1, TNF-, or LPS [106]

Zhang Y, Yan H, Lu W, Li Y, Guo X, Xu B

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DNA synthesis and cell metabolism Intracellular conversion of vitamin B 12 to two active coenzymes, in mitochondria and adenosylcobalamin in the cytoplasm, is necessary for the homeostasis of methylmalonic acid and homocysteine, respectively

The second step in the synthesis of GSH is the addition of the glycine residue to GluCys by the enzyme glutathione synthase (GS)