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SLC45A2 protein stability and regulation of melanosome pH determine melanocyte pigmentation

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Disclosure of interest: The authors acknowledge support from Boehringer Ingelheim (Angels Initiative, Australia) and Medtronic paid to the Stroke Foundation

In contrast, in the Si-IP group, a few mice models displayed moderate interstitial hypertrophy, but no interstitial hypertrophy was observed in majority of them, regardless of the administration period of MTX (Fig

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Namely anhydrolutein (B, C 40 H 54 O), 2,6,6-trimethylcyclohexa-1,4-dienylium (M1, C 9 H 13 ), (2 E ,4 E ,6 E ,8 E )-9-(4-hydroxy-2,6,6-trimethylcyclohex-1-1en-1-yl)-3,7-dimethylnona-2,4,6,8-tetraen-1-ylium (M2, C 20 H 29 O), 4-[(1 E ,3 E ,5 E ,7 E )-3,7,-dimethyldeca-1,3,5,7-tetraen-1-yl]-3,5,5-methylcyclohex-3-en-1-ol (M3, C 21 H 30 O), and zeaxanthin (M4, C 40 H 56 O) and its isomers as 13'- Z zeaxanthin, 13'- Z lutein, all- trans zeaxanthin, and 9- Z lutein