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Among the main inflammatory mediators, CRP plays a crucial role in atherogenesis by promoting complement activation, enhancing macrophage lipid uptake, stimulating pro-inflammatory cytokine release, inducing monocyte tissue factor expression, impairing endothelial function, and inhibiting nitric oxide production, further aggravating vascular injury (Shrivastava et al

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The investigators concluded that their findings suggested that dapagliflozin, when added to conventional therapy, may promote reverse remodeling and improve cardiac function in dogs with Stage C MVD

Quantitative proteomics study of protective effects of grape seed procyanidin B2 on diabetic cardiomyopathy in db/db mice

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