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The Panel conceptualized potential AEs in terms of severity, duration and reversibility

Psammaplin G ( 47 ), another bromotyrosine compound isolated from Pseudoceratina purpurea , exhibited inhibitory activity against DNMT1 with an IC 50 of 12.8 nM (Figure 9) (Pia et al., 2003)

Ulcerative colitis Seven randomized controlled trials of fish oil supplementation in patients with active ulcerative colitis reported significant improvement in at least one outcome measure, such as decreased corticosteroid use, improved disease activity scores, or improved histology scores (163)