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On the other hand, under pathological or experimental conditions with abnormally high copper, p53 eliminates copper-damaged cells to protect the organism (Xiong et al., 2023)

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193 These studies prove that PRMTs are potential targets for cancer therapy, and several PRMTs inhibitors are currently in clinical trials (Table 1)

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Ciliary neurotrophic factor activates leptin-like pathways and reduces body fat, without cachexia or rebound weight gain, even in leptin-resistant obesity