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From 15,046 genes, seven DEGs (Supplementary Data 4) were found with four significantly upregulated and three significantly downregulated in the SalA-treated group relative to the control A42-expressing Drosophila

The Tricarboxylic Acid Cycle (TCA) cycle maximizes the ATP production primarily using acetyl-CoA from glucose or fatty acids

Its expression is markedly reduced in both IBD patients and mouse models, correlating with reduced mitochondrial mass, elevated mtROS and impaired energy production [282, 283]

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GHK-Cu has been studied in clinical research showing positive effects on skin remodeling and regeneration