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Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance

239 In addition, high concentrations of calcium ions also indirectly down-regulated Mfn1 and Mfn2, further inhibited mitochondrial fusion, that ultimately promoted mitochondrial fission in senescent cells

Overall, the MD data was consistent with the markedly different dynamics observed in the cryo-EM 3DVA with the ECDs undergoing substantially greater dynamic motions in the Cagri-AMY 3 R complex than observed in the parallel rAmy-AMY 3 R complex (Supplementary Fig

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Tumor proteome analysis Tumor proteome data were generated as part of a previous study 7 and was reanalyzed for this study

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