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SKU: 31953970631
Price: 25.25 USD
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After cell adhesion, the medium was replaced, and cells were incubated with SG (CTR) or HG 35 mM for 24, 48, and 72 h

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Initially, the animals received a single intraperitoneal injection of one of the following treatments: vehicle control (0.9% normal saline or 10% DMSO), cetirizine (10 mg/kg), Icatibant (1 mg/kg), celecoxib (50 mg/kg B

Although IFN- suppresses tumor-derived chemokines to inhibit the tumor trafficking of CXCR2 + CD68 + macrophages (associated with M2 polarization) by blocking the CXCL8-CXCR2 axis, thereby counteracting immunosuppression and overcoming therapeutic resistance, dysregulated IFN signaling can promote M2-skewed macrophage polarization, which compromises the efficacy of anti-PD-1/PD-L1 therapies [299]