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found that TAT-N24, a p55PIK inhibitor, exerts significant anti-inflammatory effects in a mouse model of uveitis by inhibiting the Z-DNA binding protein (ZBP) 1-PANoptosome complex (which includes RIPK1 and RIPK3) as well as the NLRP3 inflammasome ( Figure 5 ) ( Figure 5 8 Conclusions and perspectives In recent years, uveitis research has expanded beyond a primary focus on inflammatory cell infiltration to increasingly emphasize the central role of cell death in disease initiation, progression, and resolution

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