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coli and Salmonella (Chonoles et al., 2015

While the production of one gram of cellular biomass requires 5.9 mmol of ATP, the production of 1 g of virions requires 19.6 mmol of ATP, supporting a much higher energy demand of viral replication

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Together, these results suggest that loss of PHGDH promotes mitochondrial biogenesis in macrophages

Activity (reflected by ballooning and lobular inflammation on the liver biopsy) drives disease progression and hence its diagnosis and monitoring is key for patient management, including pharmacotherapy

ROS plays a significant role in the development and function of ROs, especially in simulating and exploring retinal diseases and drug responses