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In the hippocampal TCA cycle of aging -amyloid precursor protein (APP)/Presenilin 1 (PS1) double transgenic mice, abnormal accumulations of citrate and succinate have been observed (Waddell et al

Webster RC, Coffey RJ, Kelleher RE

Unusual conjugates in biological profiles originating from consumption of onions and garlic

These models range from voluntary oral self-administration in rodents to forced vapor inhalation protocols, each capturing distinct facets of human alcoholism

We then knocked down MTHFD1 by using lentivirus containing shRNA (Lv-shM1), which did not alter the protein levels of p16, p21 and VCAM-1 in normal cultured HAECs (Fig

A total of 616 patients were randomized: 410 patients to the pemetrexed, pembrolizumab, and platinum chemotherapy arm and 206 to the placebo, pemetrexed, and platinum chemotherapy arm