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Studies have found that berberine has an antidepressant effect (Kulkarni and Dhir, 2008

In this context, earlier studies in mouse models of obesity indicated an involvement of the transcription factor p53 in regulating adipocyte stress responses that might signal to recruit macrophages 23

The experimental results showed that licochalcone A can reduce the expression of MDA, increase the synthesis of GSH, upregulate the Nrf2/HO-1 pathway, and reduce the expression of COX-2 and intracellular ROS

(2001) Glutathionylation of the p50 subunit of NF-kappaB: a mechanism for redox-induced inhibition of DNA binding

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52 The resulting loss of functional ATP7A in the intestine leads to reduced Cu efflux into the blood, an accumulation of Cu in enterocytes, and generalized severe systemic Cu deficiency