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Description

Binding of nonsubstrate ligands to the glutathione S-transferases

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These are mediated by 11-hydroxylase (P450c11 or CYP11B1), which generates cortisol (followed by activities of the ER enzymes P450c21 and P450c17), and aldosterone synthase (P450c11AS or CYP11B2) which produces aldosterone 91,92,93,94

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This can be countered by following a programme consisting of an anti-inflammatory diet and cosmeceuticals

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doi: 10.1016/j.ccell.2022.01.004 108 WangHJiangHVan De GuchtMDe RidderM

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Villiot, N., Maas, A

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