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Vitamin D: SMD: -2.54, 95% CI: -6.51,1.42

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Clinical research has demonstrated that AOD-9604 can produce meaningful metabolic effects and body composition improvements, particularly in reducing abdominal and visceral fat deposits

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Signs of B12 deficiency develop gradually and can be non-specific initially: Haematological manifestations: Macrocytic anaemia (enlarged red blood cells) Fatigue, weakness, and lethargy Pallor and shortness of breath Glossitis (inflamed, smooth tongue) Neurological and psychiatric symptoms: Paraesthesia (pins and needles) in hands and feet Peripheral neuropathy with numbness or burning sensations Ataxia and difficulty walking Memory problems and cognitive impairment Depression, irritability, or mood changes In severe cases, subacute combined degeneration of the spinal cord It is crucial to note that neurological damage can occur even in the absence of anaemia, and if left untreated, some neurological effects may become irreversible

These data not only demonstrate the anti-hypertensive effect of quercetin but also provide evidence for its role as a novel cardioprotective compound